![Zhigang Xiong, M.D, Ph.D.](/_resources/°ÄÃÅÆßÐÇͼimages/FacultyDirectoryImages/Neurobiology/ZhigangXiong.jpg)
Zhigang Xiong, M.D, Ph.D.
Professor
Neurobiology
Location: Multidisciplinary Research Center 219
Phone: 404-752-8683
E-mail: zxiong@msm.edu
Education
POSTGRADUATE:University of Toronto, School of Medicine
Postdoctoral Fellow
MEDICAL SCHOOL:
Anhui Medical University
Degree: Doctor of Medicine
GRADUATE:
University of Ottawa School of Medicine
Degree: Doctor of Philosophy in Pharmacology
Research Interests
- Ion channels
- Stroke
- Mechanisms of Neurodegeneration and Neuroprotection
Publications
- Zhou R, Leng T, Yang T, Chen F, Hu W, Xiong ZG. β-estradiol protects against acidosis-mediated and ischemic neuronal injury by promoting ASIC1a (Acid-Sensing Ion Channel 1a) protein degradation. Stroke. 50(10):2902-2911, 2019.
- Huang Y, Leng TD, Inoue K, Yang T, Liu M, Horgen FD, Fleig A, Li J, Xiong ZG. TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. J Biol Chem. 293(37):14393-14406, 2018.
- Pignataro G, Simon RP, and Xiong ZG. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischemia. Brain. 130(Pt 1): 151-8, 2006
- Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wemmie JA, Price M, Welsh MJ, and Simon RP. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell. 118(6): 687-98, 2004.
- Xiong ZG, Lu WY and MacDonald JF. Extracellular calcium sensed by a novel cation channel in hippocampal neurons. Proc. Natl. Acad. Sci. USA, 94:7014-7017, 1997.
Honors and Awards
- 2007: Established Investigator Award, American Heart Association
- 2001: Scientist Development Award, American Heart Association
- 1998: Centennial Fellowship Award, Medical Research Council of Canada
- 1996: Postdoctoral Fellowship Award, Medical Research Council of Canada